For people trying to prevent a second heart attack or stroke, evidence in support of baby aspirin therapy remains strong.
Researchers in both studies found that even low-dose aspirin carries a risk of internal gastric bleeding, and the newer study also found that older patients who were not at high risk of cardiovascular disease saw no health benefits from taking aspirin daily. The study, involving more than 19,000 people, found that the medicine was linked to a greater risk of serious...
A landmark US-Australian study has found taking aspirin daily does not improve the lifespan of people over 70, with researchers warning the costs may outweigh the benefits for healthy elderly people taking the medication to stave off various conditions.
McNeil said aspirin remains a relatively safe medication but more research was needed to investigate the long-term benefits and risks of its daily use. The researchers then followed the study's participants for a median of 4.7 years. This counted the uptick in upper gastrointestinal bleeding (HR 1.87, 95% CI 1.32-2.66) and intracranial bleeds (HR 1.50, 95% CI 1.11-2.02).
"It means millions of healthy older people around the world who are taking low dose aspirin without a medical reason, may be doing so unnecessarily", McNeil said.
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The student was led by researched at Monash University and was publishes in the New England Journal of Medicine.
Aspirin has always been used as a preventative measure to help reduce the risk of blood clots in patients who have suffered a heart attack or stroke.
A new study confirms aspirin does not help prevent a first heart attack in older adults or prolong your lifespan.
The group taking aspirin had an increased risk of death compared to the placebo group- 5.9 per cent of participants taking aspirin and 5.2 per cent taking placebo died during the study.
"I think it is time we started to phase out the use of aspirin broadly for the purposes of prevention in individuals who have not had a heart attack or stroke", said Michos, an associate professor of medicine and epidemiology and director of preventive cardiology at the Ciccarone Center for the Prevention of Heart Disease at the Johns Hopkins School of Medicine.
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The test subjects, a lot of them from Australia, were older than 70, except for blacks and Hispanics in the United States, who were recruited at age 65 or older because people in those groups have a higher risk of heart disease and cardiovascular problems than whites. "Analysis of all the cancer-related data from the trial is underway and until we have additional data, these findings should be interpreted with caution".
For cardiovascular disease, the rate was 10.7 events per 1000 person-years in the aspirin group and 11.3 events per 1000 person-years in the placebo group - also considered no difference.
"There was a small increase in the number of death overall in the aspirin group, with the largest proportion of deaths due to cancer", said Murray.
'The concern has been uncertainty about whether aspirin is beneficial for otherwise healthy older people without those conditions.
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