The scion of a decorated military family, McCain embraced his role as chairman of the Armed Services Committee, pushing for aggressive USA military intervention overseas and eager to contribute to "defeating the forces of radical Islam that want to destroy America".
Sarah Palin, who was Mr McCain's running mate during his 2008 bid for president, said the world had lost "an American original", sharing a picture of herself with the man she called her friend. "He showed us that boundless patriotism and self-sacrifice are not outdated concepts or cliches, but the building blocks of an extraordinary life".
"They key thing", Kyl added about McCain's replacement, "is to represent the state of Arizona, but also continue to represent all the people of the United States on an global level".
Mr Obama said that despite being his Democratic rival, they shared the ideals "for which generations of Americans and immigrants alike have fought, marched and sacrificed".
Obama said the two political opponents "saw our political battles, even, as a privilege, something noble, an opportunity to serve as stewards of those high ideals at home, and to advance them around the world".
President Donald Trump, who clashed with McCain over Obama-care and dealings with Russian Federation, offered his "deepest sympathies and respect" to the Republican Senator's family.
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Lim Eung-bok, who is meeting his brother and his family, said: "I have so many things I want to say but there are a lot of restrictions".
"A warrior of strength, a patriot of heart, and a man of conviction".
The sharp-tongued McCain had disagreements with many fellow politicians - including inside his own camp - but the Republican stalwart was widely recognised for his deep integrity, and condolences came swift from the highest reaches of American politics.
Former President Bill Clinton and his wife, Hillary, said in a statement: "Senator John McCain believed that every citizen has a responsibility to make something of the freedoms given by our Constitution, and from his heroic service in the Navy to his 35 years in Congress, he lived by his creed every day".
She continued: "He was a tough politician, a trusted colleague, and there will simply never be another like him".
McCain said in September that his doctors had given him a "very poor prognosis".
"Senator John McCain's remarkable record of leadership embodies his unwavering lifetime commitment to service. Canadians join Americans tonight in celebrating his life and mourning his passing".
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While OSU opens at No. 5, it is the Wisconsin Badgers one spot ahead of them who take the top spot among B1G teams. No. 5 Ohio State, No. 10 Penn State, No. 11 Michigan State and No. 14 Michigan round out the Big Ten contingent.
McCain ran twice for President. "Senator John McCain was a maverick and a fighter, never afraid to stand for his beliefs".
Sen. Lindsey Graham, a South Carolina Republican who's one of McCain's closest friends, said on Twitter that Cindy McCain "remains steadfast and is traveling every step of the way on this hard journey", and the "love provided by Meghan and the McCain children to their father has been comforting to witness". McCain was first elected to office in 1982, when he won a seat in the U.S. House of Representatives from Arizona.
"May he rest in peace".
Sen. Bernie Sanders tweeted: "As you go through life, you meet few truly great people". Israel's prime minister, Benjamin Netanyahu, said McCain's support for the Jewish state "never wavered".
Flake also said that he "admired" McCain's dramatic "no" vote on repealing the Affordable Care Act in July of previous year despite voting the other way, as well as McCain's emphasis on senators working together across party lines.
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In February, Saudi Arabia freed nine Iranian fishermen detained for two years, accusing them of entering its waters. OPEC expects non-OPEC supply to expand by 2.13 million bpd next year, 30,000 bpd more than forecast last month.